Nguyễn An Ninh’s Anti-Colonial Thought: A New Account of National Shame

A source of national shame can be the perception that one’s nation is intellectually inferior to other nations. This kind of national shame can lead not to despair but to a sense of national responsibility to engage in creative self-renewal and to create national identity from scratch. An exemplar of someone who recognized and engaged with this kind of national shame is Nguyễn An Ninh (1900–1943), an influential Vietnamese anti-colonial intellectual in French colonial Vietnam. Ninh’s account of national shame challenges existing assumptions in political theory, namely that national identity requires national pride, that national shame comes from bad actions towards outside groups, and that national responsibility means responsibility for those bad actions. Postcolonial and decolonial literature have tended to attribute any perception of inferiority on the part of the colonized to “internalized inferiority,” and to assume the existence of an indigenous “original” culture that colonizers destroy, overlooking the fact that natives themselves sometimes questioned the existence of “original” culture. Ninh shows that colonized people can be ashamed of lacking intellectual culture on their own terms and be anti-colonial at the same time

TRAP CHARACTERIZATION IN HIGH FIELD, HIGH TEMPERATURE STRESSED GALLIUM NITRIDE HIGH ELECTRON MOBILITY TRANSISTORS

Gallium Nitride (GaN) high electron mobility transistors (HEMTs) offer higher power output over existing technology. However, issues such as current collapse and kink effect hinder GaN HEMTs performance. The degraded performance is linked to traps within the device. Capacitance-voltage (C-V) and current-voltage (I-V) measurements were performed on commercially available GaN-on-Si to characterize traps before and after high field, high temperature stressed conditions. The results revealed the devices had less gate current leakage after stressing and the C-V characteristics changed dramatically after a 24 hour recovery period.http://archive.org/details/trapcharacteriza1094532885Civilian, United States Air ForceApproved for public release; distribution is unlimited

extremefit: A Package for Extreme Quantiles

extremefit is a package to estimate the extreme quantiles and probabilities of rare events. The idea of our approach is to adjust the tail of the distribution function over a threshold with a Pareto distribution. We propose a pointwise data driven procedure to choose the threshold. To illustrate the method, we use simulated data sets and three real-world data sets included in the package

A comparative evaluation of interactive segmentation algorithms

In this paper we present a comparative evaluation of four popular interactive segmentation algorithms. The evaluation was carried out as a series of user-experiments, in which participants were tasked with extracting 100 objects from a common dataset: 25 with each algorithm, constrained within a time limit of 2 min for each object. To facilitate the experiments, a “scribble-driven” segmentation tool was developed to enable interactive image segmentation by simply marking areas of foreground and background with the mouse. As the participants refined and improved their respective segmentations, the corresponding updated segmentation mask was stored along with the elapsed time. We then collected and evaluated each recorded mask against a manually segmented ground truth, thus allowing us to gauge segmentation accuracy over time. Two benchmarks were used for the evaluation: the well-known Jaccard index for measuring object accuracy, and a new fuzzy metric, proposed in this paper, designed for measuring boundary accuracy. Analysis of the experimental results demonstrates the effectiveness of the suggested measures and provides valuable insights into the performance and characteristics of the evaluated algorithms

An Expressive Robotic Table to Enhance Social Interactions

We take initial steps into prototyping an expressive robotic table that can serve as a social mediator. The work is constructed through a rapid prototyping process consisting of five workshopbased phases with five interaction design participants. We report on the various prototyping techniques that led to the generated concept of an expressive robotic table. Our design process explores how expressive motion cues such as respiratory movements can be leveraged to mediate social interactions between people in cold outdoor environments. We conclude by discussing the implications of the different prototyping methods applied and the envisioned future directions of the work within the scope of expressive robotics

Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.

Staphylococcus aureus is both an important pathogen and a human commensal. To explore this ambivalent relationship between host and microbe, we analysed the memory humoral response against IsdB, a protein involved in iron acquisition, in four healthy donors. Here we show that in all donors a heavily biased use of two immunoglobulin heavy chain germlines generated high affinity (pM) antibodies that neutralize the two IsdB NEAT domains, IGHV4-39 for NEAT1 and IGHV1-69 for NEAT2. In contrast to the typical antibody/antigen interactions, the binding is primarily driven by the germline-encoded hydrophobic CDRH-2 motifs of IGHV1-69 and IGHV4-39, with a binding mechanism nearly identical for each antibody derived from different donors. Our results suggest that IGHV1-69 and IGHV4-39, while part of the adaptive immune system, may have evolved under selection pressure to encode a binding motif innately capable of recognizing and neutralizing a structurally conserved protein domain involved in pathogen iron acquisition

Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways

AbstractThe RNase III enzyme Dicer processes RNA into siRNAs and miRNAs, which direct a RNA-induced silencing complex (RISC) to cleave mRNA or block its translation (RNAi). We have characterized mutations in the Drosophila dicer-1 and dicer-2 genes. Mutation in dicer-1 blocks processing of miRNA precursors, whereas dicer-2 mutants are defective for processing siRNA precursors. It has been recently found that Drosophila Dicer-1 and Dicer-2 are also components of siRNA-dependent RISC (siRISC). We find that Dicer-1 and Dicer-2 are required for siRNA-directed mRNA cleavage, though the RNase III activity of Dicer-2 is not required. Dicer-1 and Dicer-2 facilitate distinct steps in the assembly of siRISC. However, Dicer-1 but not Dicer-2 is essential for miRISC-directed translation repression. Thus, siRISCs and miRISCs are different with respect to Dicers in Drosophila